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Consolidated Statements of Operations (Parenthetical) - Astellas Agreement [Member] - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
License and milestone revenue from a related party $ 108,434 $ 14,323 $ 129,405
Collaboration services and other revenue from a related party 21,928 19,174 29,393
Product revenue from a related party 35,568 0 0
Drug product revenue from a related party $ 3,186 $ 4,281 $ (36,324)