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Collaboration Agreements, License Agreement and Revenues - Eluminex Agreement - Additional Information 2 (Detail) $ in Thousands | 1 Months Ended | 12 Months Ended
--- | --- | ---
Jul. 31, 2021 USD ($) PerformanceObligation | Dec. 31, 2021 USD ($) | Dec. 31, 2020 USD ($) | Dec. 31, 2019 USD ($)
Revenue Recognition Multiple Deliverable Arrangements [Line Items] |  |  |  |
Total revenue |  | $ 235,309 | $ 176,319 | $ 256,577
Eluminex [Member] |  |  |  |
Revenue Recognition Multiple Deliverable Arrangements [Line Items] |  |  |  |
Upfront payment | $ 8,000 | 8,000 |  |
Future manufacturing clinical regulatory and commercial milestone payments | 64,000 |  |  |
Commercial milestone | $ 36,000 |  |  |
Total revenue |  | $ 8,000 |  |
Eluminex [Member] | ASC 606 [Member] |  |  |  |
Revenue Recognition Multiple Deliverable Arrangements [Line Items] |  |  |  |
Number of identified performance obligation at inception of agreement | PerformanceObligation | 1 |  |  |
Eluminex [Member] | Cornea Products [Member] | ASC 606 [Member] |  |  |  |
Revenue Recognition Multiple Deliverable Arrangements [Line Items] |  |  |  |
Percentage of product manufacturing costs until manufacturing technology fully transferred | 110.00% |  |  |

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