Collaborative arrangement aggregate consideration for milestone and upfront payments.

No definition available.

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Period Type:	instant

- Definition

Commercial milestone.

+ References

No definition available.

+ Details

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Balance Type:	credit
Period Type:	duration

- Definition

Future manufacturing clinical regulatory and commercial milestone payments.

+ References

No definition available.

+ Details

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- Definition

Number of identified performance obligation at inception of agreement.

+ References

No definition available.

+ Details

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- Definition

Percentage of product manufacturing costs until manufacturing technology fully transferred.

+ References

No definition available.

+ Details

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- Definition

Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 30
-Subparagraph (a)
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Reference 2: http://www.xbrl.org/2003/role/disclosureRef
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+ Details

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- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

No definition available.

+ Details

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- Details

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- Details

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- Details

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Collaboration Agreements, License Agreement and Revenues - Eluminex Agreement - Additional Information 2 (Detail) $ in Thousands	1 Months Ended	12 Months Ended
	Jul. 31, 2021 USD ($) PerformanceObligation	Dec. 31, 2021 USD ($)	Dec. 31, 2020 USD ($)	Dec. 31, 2019 USD ($)
Revenue Recognition Multiple Deliverable Arrangements [Line Items]
Total revenue		$ 235,309	$ 176,319	$ 256,577
Eluminex [Member]
Revenue Recognition Multiple Deliverable Arrangements [Line Items]
Upfront payment	$ 8,000	8,000
Future manufacturing clinical regulatory and commercial milestone payments	64,000
Commercial milestone	$ 36,000
Total revenue		$ 8,000
Eluminex [Member] \| ASC 606 [Member]
Revenue Recognition Multiple Deliverable Arrangements [Line Items]
Number of identified performance obligation at inception of agreement \| PerformanceObligation	1
Eluminex [Member] \| Cornea Products [Member] \| ASC 606 [Member]
Revenue Recognition Multiple Deliverable Arrangements [Line Items]
Percentage of product manufacturing costs until manufacturing technology fully transferred	110.00%