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Balance Sheet Components - Schedule of Accrued and Other Current Liabilities (Detail) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Accrued Liabilities Current [Abstract]
Preclinical and clinical trial accruals	$ 56,283	$ 44,113
Acquired in-process research and development asset	35,000	0
Payroll and related accruals	20,909	22,800
Contract liabilities to pharmaceutical distributors	3,176	15,137
Accrued co-promotion expenses - current	25,746	11,537
Roxadustat profit share to AstraZeneca	7,895	7,007
Property taxes and other taxes	12,610	5,970
Professional services	6,074	4,869
Other	4,895	6,900
Total accrued and other current liabilities	$ 172,588	$ 118,333

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Accrued co-promotion expenses - current.

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Total of the carrying values as of the balance sheet date of obligations incurred through that date and payable for obligations related to pre-clinical and clinical trial activities, including those performed by third parties. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).

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Property taxes and other current.

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Carrying value as of the balance sheet date of obligations incurred and payable, pertaining to costs that are statutory in nature, are incurred on contractual obligations, or accumulate over time and for which invoices have not yet been received or will not be rendered. Examples include taxes, interest, rent and utilities. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).

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-SubTopic 10
-Section S99
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Carrying value as of the balance sheet date of obligations incurred through that date and payable for professional fees, such as for legal and accounting services received. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).

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Amount of expenses incurred but not yet paid classified as other, due within one year or the normal operating cycle, if longer.

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