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Related Party Transactions - Additional Information (Detail) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021	Dec. 31, 2021
Related Party Transaction [Line Items]
Accounts Receivable Related Parties Current	$ 38,755		$ 10,930
Accrued liabilities to related party	49,677		4
Investment income (loss)	(320)	$ 240
Equity method investments	4,155		3,825
Astellas [Member]
Related Party Transaction [Line Items]
Drug product revenue from a related party	7,600	4,000
Astellas [Member] | Collaborative Arrangement [Member]
Related Party Transaction [Line Items]
Revenue related to collaboration agreements	27,800	3,600
Accounts Receivable Related Parties Current	37,600		10,900
Accrued liabilities to related party	49,700
Contract With Customer Liability	29,600		27,900
Falikang [Member]
Related Party Transaction [Line Items]
Accounts Receivable Related Parties Current	1,200		0
Investment income (loss)	300	(200)
Equity method investments	$ 4,200		3,800
Percentage of outstanding shares owned	51.10%
Deferred revenue	$ 0		$ 1,200
Falikang [Member] | Collaborative Arrangement [Member]
Related Party Transaction [Line Items]
Revenue related to collaboration agreements	$ 16,200	$ 10,400

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