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Balance Sheet Components - Schedule of Accrued and Other Current Liabilities (Detail) - USD ($)
$ in Thousands
Jun. 30, 2022
Dec. 31, 2021
Accrued Liabilities, Current [Abstract]    
Preclinical and clinical trial accruals $ 66,553 $ 56,283
API and bulk drug product price true-up 54,443
Acquired in-process research and development asset 35,000
Payroll and related accruals 13,480 20,909
Accrued co-promotion expenses - current 1,402 3,176
Contract liabilities to pharmaceutical distributors 7,497 7,895
Roxadustat profit share to AstraZeneca 32,352 25,746
Property taxes and other taxes 5,449 12,610
Professional services 4,929 6,074
Other 6,994 4,906
Total accrued and other current liabilities $ 193,099 $ 172,599