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Related Party Transactions - Additional Information (Detail) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021	Dec. 31, 2021
Related Party Transaction [Line Items]
Accounts Receivable, Related Parties, Current	$ 26,779		$ 26,779		$ 10,930
Accrued liabilities to related party	43,286		43,286		4
Investment income (loss)	(565)	$ (562)	(885)	$ (323)
Equity method investments	4,494		4,494		3,825
Astellas [Member]
Related Party Transaction [Line Items]
Drug product revenue from a related party	1,100	(2,000)	8,700	2,100
Astellas [Member] | Collaborative Arrangement [Member]
Related Party Transaction [Line Items]
Revenue related to collaboration agreements	1,800	2,600	29,600	6,300
Accounts Receivable, Related Parties, Current	26,100		26,100		10,900
Accrued liabilities to related party	43,300		43,300
Contract with Customer, Liability	54,900		54,900		27,900
Falikang [Member]
Related Party Transaction [Line Items]
Accounts Receivable, Related Parties, Current	700		700		0
Investment income (loss)	600	600	(900)	(300)
Equity method investments	4,500		$ 4,500		3,800
Percentage of outstanding shares owned			51.10%
Deferred revenue	0		$ 0		$ 1,200
Falikang [Member] | Collaborative Arrangement [Member]
Related Party Transaction [Line Items]
Revenue related to collaboration agreements	$ 19,700	$ 11,800	$ 36,000	$ 22,200

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