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v3.22.2.2

Collaboration Agreements, License Agreement and Revenues - Roll-forward of Related Contract Liabilities (Detail) $ in Thousands | 9 Months Ended
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Sep. 30, 2022 USD ($)
AstraZeneca Agreements [Member] |
Contract with Customer Liability [Line Items] |
Balance at December 31, 2021 | $ (171,516)
Additions | (57,846)
Currency Translation and Other | 3,051
Recognized as Revenue | 50,873
Balance at June 30, 2022 | (175,438)
Product Revenue, Net [Member] | Direct Sales [Member] | Contract Liabilities [Member] |
Contract with Customer Liability [Line Items] |
Balance at December 31, 2021 | (3,176)
Additions | (537)
Deduction | 2,754
Currency Translation and Other | 226
Balance at June 30, 2022 | (733)
Drug Product Revenue [Member] |
Contract with Customer Liability [Line Items] |
Balance at December 31, 2021 | (39,036)
Additions | (74,635)
Reclassified to Accrued Liability | 66,361
Recognized as Revenue | 326
Balance at June 30, 2022 | (46,984)
Drug Product Revenue [Member] | AstraZeneca Agreements [Member] | U.S. [Member] |
Contract with Customer Liability [Line Items] |
Balance at December 31, 2021 | (11,171)
Additions | 0
Reclassified to Accrued Liability | 11,171
Recognized as Revenue | 0
Balance at June 30, 2022 | 0
Drug Product Revenue [Member] | Astellas Agreement [Member] | Japan [Member] |
Contract with Customer Liability [Line Items] |
Balance at December 31, 2021 | (1,974)
Additions | (2,226)
Reclassified to Accrued Liability | 4,200
Recognized as Revenue | 0
Balance at June 30, 2022 | 0
Drug Product Revenue [Member] | Astellas Agreement [Member] | Europe [Member] |
Contract with Customer Liability [Line Items] |
Balance at December 31, 2021 | (25,891)
Additions | (72,409)
Reclassified to Accrued Liability | 50,990
Recognized as Revenue | 326
Balance at June 30, 2022 | $ (46,984)

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