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Collaboration Agreements, License Agreement and Revenues - Transaction Price Related to Consideration Received and Accounts Receivable Allocated to Performance Obligations Deferred Revenue (Parenthetical) (Detail) - USD ($) $ in Thousands | Sep. 30, 2022 | Dec. 31, 2021
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Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |
Deferred revenue, net of current ($42,278 and $25,891 to a related party) | $ 199,758 | $ 186,801
AstraZeneca Agreements [Member] |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |
Deferred Revenue | 175,438 | $ 171,516
AstraZeneca Agreements [Member] | U.S./RoW [Member] |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |
Deferred revenue, net of current ($42,278 and $25,891 to a related party) | 160,100 |
Deferred Revenue | 175,400 |
Net unbilled co-development revenue | $ 15,300 |

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