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Collaboration Agreements, License Agreement and Revenues - Transaction Price Related to Consideration Received and Accounts Receivable Allocated to Performance Obligations Deferred Revenue (Parenthetical) (Detail) - USD ($) $ in Thousands | Dec. 31, 2022 | Dec. 31, 2021
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Revenue Recognition Multiple Deliverable Arrangements [Line Items] |  |
Deferred revenue, net of current | $ 185,722 | $ 186,801
Net unbilled co-development revenue | 0 | 8,000
AstraZeneca Agreements [Member] |  |
Revenue Recognition Multiple Deliverable Arrangements [Line Items] |  |
Deferred Revenue | 175,646 | 171,516
Net unbilled co-development revenue | 17,500 | $ 9,100
AstraZeneca Agreements [Member] | U.S./RoW [Member] |  |
Revenue Recognition Multiple Deliverable Arrangements [Line Items] |  |
Deferred revenue, net of current | 158,200 |
Deferred Revenue | 175,600 |
Net unbilled co-development revenue | $ 17,500 |

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