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Related Party Transactions - Additional Information (Detail) - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2020
Related Party Transaction [Line Items] |  |  |
Accounts receivable from related parties | $ 12,088 | $ 10,930 |
Accrued liabilities to related party | 63,886 | 4 |
Investment income (loss) | 1,573 | 1,007 | $ (202)
Equity method investment in unconsolidated variable interest entity | 5,061 | 3,825 |
Astellas [Member] |  |  |
Related Party Transaction [Line Items] |  |  |
Drug product revenue from a related party | 11,100 | 3,200 | 4,300
Astellas [Member] | Collaborative Arrangement [Member] |  |  |
Related Party Transaction [Line Items] |  |  |
Accounts receivable from related parties | 1,500 | 10,900 |
Deferred revenue | 40,300 | 27,900 |
Accrued liabilities to related party | 63,900 |  |
Falikang |  |  |
Related Party Transaction [Line Items] |  |  |
Accounts receivable from related parties | 10,500 | 0 |
Deferred revenue | $ 0 | 1,200 |
Percentage of outstanding shares owned | 51.10% |  |
Investment income (loss) | $ 1,600 | 1,000 | (200)
Equity method investment in unconsolidated variable interest entity | 5,100 | 3,800 |
Falikang | Collaborative Arrangement [Member] |  |  |
Related Party Transaction [Line Items] |  |  |
Revenue related to collaboration agreements | 71,200 | 35,600 |
License and Development [Member] | Astellas [Member] | Collaborative Arrangement [Member] |  |  |
Related Party Transaction [Line Items] |  |  |
Revenue related to collaboration agreements | $ 32,500 | $ 130,400 | $ 33,500

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