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v3.22.4

Collaboration Agreements,License Agreement and Revenues - Roll-forward of Related Contract Liabilities (Detail) $ in Thousands | 12 Months Ended
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Dec. 31, 2022 USD ($)
AstraZeneca Agreements [Member] |
Contract with Customer Liability [Line Items] |
Balance at December 31, 2021 | $ (171,516)
Additions | (77,195)
Currency Translation and Other | 1,898
Recognized as Revenue | 71,167
Balance at December 31, 2022 | (175,646)
Product [Member] | Direct Sales [Member] | Contract Liabilities [Member] |
Contract with Customer Liability [Line Items] |
Balance at December 31, 2021 | (3,176)
Additions | (653)
Deduction | 3,222
Currency Translation and Other | 217
Balance at December 31, 2022 | (390)
Drug Product Revenue [Member] |
Contract with Customer Liability [Line Items] |
Balance at December 31, 2021 | (39,036)
Additions | (74,634)
Recognized as Revenue | 619
Reclassified to accrued liability / accounts payable | 72,748
Balance at December 31, 2022 | (40,303)
Drug Product Revenue [Member] | AstraZeneca Agreements [Member] | U.S. [Member] |
Contract with Customer Liability [Line Items] |
Balance at December 31, 2021 | (11,171)
Additions | 0
Recognized as Revenue | 0
Reclassified to accrued liability / accounts payable | 11,171
Balance at December 31, 2022 | 0
Drug Product Revenue [Member] | Astellas Agreement | Japan [Member] |
Contract with Customer Liability [Line Items] |
Balance at December 31, 2021 | (1,974)
Additions | (2,226)
Recognized as Revenue | 0
Reclassified to accrued liability / accounts payable | 4,200
Balance at December 31, 2022 | 0
Drug Product Revenue [Member] | Astellas Agreement | Europe [Member] |
Contract with Customer Liability [Line Items] |
Balance at December 31, 2021 | (25,891)
Additions | (72,408)
Recognized as Revenue | 619
Reclassified to accrued liability / accounts payable | 57,377
Balance at December 31, 2022 | $ (40,303)

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