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Related Party Transactions - Additional Information (Detail) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Related Party Transaction [Line Items]
Accounts receivable from related parties	$ 12,088	$ 10,930
Accrued liabilities to related party	63,886	4
Investment income (loss)	1,573	1,007	$ (202)
Equity method investment in unconsolidated variable interest entity	5,061	3,825
Astellas [Member]
Related Party Transaction [Line Items]
Drug product revenue from a related party	11,100	3,200	4,300
Astellas [Member] | Collaborative Arrangement [Member]
Related Party Transaction [Line Items]
Accounts receivable from related parties	1,500	10,900
Deferred revenue	40,300	27,900
Accrued liabilities to related party	63,900
Falikang
Related Party Transaction [Line Items]
Accounts receivable from related parties	10,500	0
Deferred revenue	$ 0	1,200
Percentage of outstanding shares owned	51.10%
Investment income (loss)	$ 1,600	1,000	(200)
Equity method investment in unconsolidated variable interest entity	5,100	3,800
Falikang | Collaborative Arrangement [Member]
Related Party Transaction [Line Items]
Revenue related to collaboration agreements	71,200	35,600
License and Development [Member] | Astellas [Member] | Collaborative Arrangement [Member]
Related Party Transaction [Line Items]
Revenue related to collaboration agreements	$ 32,500	$ 130,400	$ 33,500

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