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Balance Sheet Components - Schedule of Property and Equipment (Detail) - USD ($) $ in Thousands	Dec. 31, 2022	Dec. 31, 2021
Property Plant And Equipment [Line Items]
Property and equipment, gross	$ 149,287	$ 149,285
Less: accumulated depreciation	(128,682)	(121,008)
Property and equipment, net	20,605	28,277
Leasehold improvements [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	102,580	103,352
Laboratory Equipment [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	21,175	19,300
Machinery [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	9,642	8,339
Computer Equipment [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	9,486	9,670
Furniture and Fixtures [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	6,200	6,201
Construction in progress [Member]
Property Plant And Equipment [Line Items]
Property and equipment, gross	$ 204	$ 2,423

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- Definition

Amount of accumulated depreciation, depletion and amortization for physical assets used in the normal conduct of business to produce goods and services.

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