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v3.23.1

Condensed Consolidated Statement of Cash Flows (Unaudited) - USD ($) $ in Thousands | 3 Months Ended
--- | ---
Mar. 31, 2023 | Mar. 31, 2022
Operating activities |  |
Net loss | $ (76,705) | $ (63,205)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation | 2,542 | 2,450
Amortization of finance lease right-of-use assets | 423 | 134
Net accretion of premium and discount on investments | (689) | 928
Investment income in unconsolidated variable interest entity | (796) | (320)
Loss on disposal of property and equipment | 1 | 5
Stock-based compensation | 16,112 | 17,152
Non-cash interest expense related to sale of future revenues | 2,249 | 0
Impairment of investment | 1,000 | 0
Realized loss on sales of available-for-sale securities | 271 | 5
Changes in operating assets and liabilities: |  |
Accounts receivable, net | (1,299) | (26,481)
Inventories | (1,940) | (12,000)
Prepaid expenses and other current assets | 38 | 11,382
Operating lease right-of-use assets | 3,237 | 3,132
Other assets | 1,072 | (459)
Accounts payable | 40,473 | 10,207
Accrued and other liabilities | (66,266) | 65,993
Operating lease liabilities, current | (371) | 31
Deferred revenue | (18,877) | (13,024)
Accrued interest for finance lease liabilities | (56) | (21)
Operating lease liabilities, non-current | (2,720) | (2,835)
Other long-term liabilities | 710 | (1,550)
Net cash used in operating activities | (101,591) | (8,476)
Investing activities |  |
Purchases of property and equipment | (591) | (1,638)
Payment made for acquired in-process research and development asset | 0 | (35,000)
Purchases of available-for-sale securities | (2,472) | (20,912)
Proceeds from sales of available-for-sale securities | 1,730 | 7,382
Proceeds from maturities of investments | 104,815 | 76,103
Net cash provided by investing activities | 103,482 | 25,935
Financing activities |  |
Repayments of finance lease liabilities | (71) | (1)
Repayments of lease obligations | (101) | (101)
Cash paid for payroll taxes on restricted stock unit releases | 0 | (2,974)
Proceeds from issuance of common stock under ATM Program, net of commissions | 30,750 | 0
Proceeds from issuance of common stock under employee stock plans | 907 | 183
Net cash provided by (used in) financing activities | 31,485 | (2,893)
Effect of exchange rate change on cash and cash equivalents | (526) | 107
Net increase in cash and cash equivalents | 32,850 | 14,673
Total cash and cash equivalents at beginning of period | 155,700 | 171,223
Total cash and cash equivalents at end of period | $ 188,550 | $ 185,896

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