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Collaboration Agreements, License Agreement and Revenues - Summary of Revenue Recognized Under the Collaboration Agreements - Additional Information 4 (Detail) | 3 Months Ended
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Mar. 31, 2023 USD ($)
Europe [Member] | Astellas Agreement [Member] |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Transaction price, variable consideration from estimated future co-development billing | $ 5,800,000
Changes in revenue from changes to estimated variable consideration | 0
U.S./RoW and China [Member] |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |
Transaction price, variable consideration from estimated future co-development billing | 9,800,000
Changes in revenue from changes to estimated variable consideration | $ 0

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