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Collaboration Agreements, License Agreement and Revenues - Transaction Price Related to Consideration Received and Accounts Receivable Allocated to Performance Obligations Deferred Revenue (Parenthetical) (Detail) - USD ($) $ in Thousands | Mar. 31, 2023 | Dec. 31, 2022
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Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |
Deferred revenue, net of current | $ 163,089 | $ 185,722
AstraZeneca Agreements [Member] |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |
Deferred Revenue | 175,326 | $ 175,646
AstraZeneca Agreements [Member] | U.S./RoW [Member] |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |
Deferred revenue, net of current | 156,200 |
Deferred Revenue | 175,300 |
Net unbilled co-development revenue | $ 19,100 |

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