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Balance Sheet Components - Schedule of Accrued and Other Current Liabilities (Detail) - USD ($) $ in Thousands	Mar. 31, 2023	Dec. 31, 2022
Accrued Liabilities, Current [Abstract]
Preclinical and clinical trial accruals	$ 42,953	$ 57,780
API and bulk drug product price true-up	30,758	75,055
Payroll and related accruals	12,230	22,562
Accrued co-promotion expenses - current	36,688	36,677
Roxadustat profit share to AstraZeneca	7,311	7,280
Property taxes and other taxes	8,041	7,691
Professional services	8,354	5,480
Current portion of liability related to sale of future revenues	3,212	0
Other	7,495	7,248
Total accrued and other current liabilities	$ 157,042	$ 219,773

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- Definition

Accrued API and bulk drug product price true-up current.

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Accrued co-promotion expenses - current.

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- Definition

Total of the carrying values as of the balance sheet date of obligations incurred through that date and payable for obligations related to pre-clinical and clinical trial activities, including those performed by third parties. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).

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Accrued profit share current.

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Liability related to sale of future revenues current.

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Property taxes and other current.

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Carrying value as of the balance sheet date of obligations incurred and payable, pertaining to costs that are statutory in nature, are incurred on contractual obligations, or accumulate over time and for which invoices have not yet been received or will not be rendered. Examples include taxes, interest, rent and utilities. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02.20)
-URI https://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682

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Carrying value as of the balance sheet date of obligations incurred through that date and payable for professional fees, such as for legal and accounting services received. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02.20)
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Total of the carrying values as of the balance sheet date of obligations incurred through that date and payable for obligations related to services received from employees, such as accrued salaries and bonuses, payroll taxes and fringe benefits. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).

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-Publisher FASB
-Name Accounting Standards Codification
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-SubTopic 10
-Section S99
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-Subparagraph (SX 210.5-02.20)
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Amount of expenses incurred but not yet paid classified as other, due within one year or the normal operating cycle, if longer.

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-Name Accounting Standards Codification
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-SubTopic 10
-Section S99
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-URI https://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682

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