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Collaboration Agreements, License Agreement and Revenues - Summary of License Revenue and Development Revenue Recognized under Agreement (Detail) - USD ($) $ in Thousands | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2023 | Sep. 30, 2022 | Sep. 30, 2023 | Sep. 30, 2022
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |  |  |
Total revenue | $ 40,134 | $ 15,735 | $ 120,614 | $ 106,367
License Revenue [Member] |  |  |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |  |  |
Total revenue | 2,649 | 0 | 9,649 | 22,590
Development Revenue [Member] |  |  |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |  |  |
Total revenue | 6,775 | 2,453 | 15,825 | 19,672
Astellas Agreement [Member] | License Revenue [Member] | Europe [Member] |  |  |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |  |  |
Total revenue | 0 | 0 | 0 | 22,590
Astellas Agreement [Member] | Development Revenue [Member] | Japan [Member] |  |  |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |  |  |
Total revenue | 36 | 45 | 164 | 156
Astellas Agreement [Member] | Development Revenue [Member] | Europe [Member] |  |  |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |  |  |
Total revenue | 2,322 | 1,369 | 5,657 | 8,263
AstraZeneca Agreements [Member] | License Revenue [Member] | U.S./RoW and China [Member] |  |  |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |  |  |
Total revenue | 2,649 | 0 | 2,649 | 0
AstraZeneca Agreements [Member] | Development Revenue [Member] | U.S./RoW and China [Member] |  |  |  |
Revenue Recognition, Multiple-deliverable Arrangements [Line Items] |  |  |  |
Total revenue | $ 3,676 | $ 579 | $ 7,981 | $ 9,750

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