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Collaboration Agreements, License Agreement and Revenues - AstraZeneca Agreements - Additional Information 1 (Detail) - USD ($) $ in Thousands |  | 12 Months Ended |
--- | --- | --- | ---
Jul. 30, 2013 | Dec. 31, 2023 | Dec. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2015 | Sep. 18, 2023
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Deferred Revenue |  | $ 12,740 | $ 12,739 |  |  |
Deferred revenue ($7,220 and $9,259 to related parties) |  | 12,740 | 12,739 |  |  |
Total revenue |  | 147,752 | 140,734 | $ 235,309 |  |
Product Revenue, Net [Member] |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Total revenue |  | 100,949 | 82,869 | 47,638 |  |
Drug Product Revenue, Net [Member] |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Total revenue |  | 18,753 | 11,086 | 962 |  |
China [Member] |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Recognized as Revenue |  | 500 |  |  |  |
AstraZeneca Agreements [Member] |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Recognized as Revenue |  | 89,055 |  |  |  |
AstraZeneca Agreements [Member] | Selling, General and Administrative Expenses [Member] |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Co-promotion expenses |  | 4,600 | 4,400 | 4,700 |  |
AstraZeneca Agreements [Member] | U.S./RoW [Member] |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Upfront, non-contingent, non-refundable and time-based payments | $ 374,000 |  |  |  |  |
Potential milestone payments | 875,000 |  |  |  |  |
Commercial sales milestone | 325,000 |  |  |  |  |
Shared development costs |  |  |  |  | $ 233,000 |
Aggregate considerations received excluding drug product revenue |  | 439,000 |  |  |  |
AstraZeneca Agreements [Member] | U.S./RoW [Member] | FibroGen, Inc. [Member] |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Shared development costs |  |  |  |  | $ 116,500 |
AstraZeneca Agreements [Member] | U.S./RoW [Member] | Clinical and Development Milestone [Member] |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Potential milestone payments | 65,000 |  |  |  |  |
AstraZeneca Agreements [Member] | U.S./RoW [Member] | Regulatory Milestone [Member] |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Potential milestone payments | 325,000 |  |  |  |  |
AstraZeneca Agreements [Member] | U.S./RoW [Member] | Deferred Approval Milestone [Member] |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Potential milestone payments | 160,000 |  |  |  |  |
AstraZeneca Agreements [Member] | China [Member] |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Potential milestone payments | 348,500 |  |  |  |  |
Transaction price and allocated to performance obligations |  |  |  |  |  | $ 4,000
Proceeds from upfront, non-contingent and non-refundable payments | 28,200 |  |  |  |  |
Commercial sales and other events milestone | 187,500 |  |  |  |  |
Aggregate considerations received |  | 77,200 |  |  |  |
Recognized as Revenue |  | 3,500 |  |  |  |
Contract asset |  | 4,000 |  |  |  |
AstraZeneca Agreements [Member] | China [Member] | Accrued and Other Current Liabilities [Member] |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Deferred Revenue |  | 7,100 | 7,300 |  |  |
Deferred revenue ($7,220 and $9,259 to related parties) |  | 7,100 | 7,300 |  |  |
AstraZeneca Agreements [Member] | China [Member] | Clinical and Development Milestone [Member] |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Potential milestone payments | 15,000 |  |  |  |  |
AstraZeneca Agreements [Member] | China [Member] | Regulatory Milestone [Member] |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Potential milestone payments | $ 146,000 |  |  |  |  |
Direct Sales [Member] | Product Revenue, Net [Member] |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Total revenue |  | $ 11,894 | $ 11,702 | $ 12,070 |  |

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