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Collaboration Agreements, License Agreement and Revenues - AstraZeneca Agreements - Additional Information 1 (Detail) - USD ($) $ in Thousands		12 Months Ended
	Jul. 30, 2013	Dec. 31, 2023	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2015	Sep. 18, 2023
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Deferred Revenue		$ 12,740	$ 12,739
Deferred revenue ($7,220 and $9,259 to related parties)		12,740	12,739
Total revenue		147,752	140,734	$ 235,309
Product Revenue, Net [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Total revenue		100,949	82,869	47,638
Drug Product Revenue, Net [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Total revenue		18,753	11,086	962
China [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Recognized as Revenue		500
AstraZeneca Agreements [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Recognized as Revenue		89,055
AstraZeneca Agreements [Member] | Selling, General and Administrative Expenses [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Co-promotion expenses		4,600	4,400	4,700
AstraZeneca Agreements [Member] | U.S./RoW [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Upfront, non-contingent, non-refundable and time-based payments	$ 374,000
Potential milestone payments	875,000
Commercial sales milestone	325,000
Shared development costs					$ 233,000
Aggregate considerations received excluding drug product revenue		439,000
AstraZeneca Agreements [Member] | U.S./RoW [Member] | FibroGen, Inc. [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Shared development costs					$ 116,500
AstraZeneca Agreements [Member] | U.S./RoW [Member] | Clinical and Development Milestone [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Potential milestone payments	65,000
AstraZeneca Agreements [Member] | U.S./RoW [Member] | Regulatory Milestone [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Potential milestone payments	325,000
AstraZeneca Agreements [Member] | U.S./RoW [Member] | Deferred Approval Milestone [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Potential milestone payments	160,000
AstraZeneca Agreements [Member] | China [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Potential milestone payments	348,500
Transaction price and allocated to performance obligations						$ 4,000
Proceeds from upfront, non-contingent and non-refundable payments	28,200
Commercial sales and other events milestone	187,500
Aggregate considerations received		77,200
Recognized as Revenue		3,500
Contract asset		4,000
AstraZeneca Agreements [Member] | China [Member] | Accrued and Other Current Liabilities [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Deferred Revenue		7,100	7,300
Deferred revenue ($7,220 and $9,259 to related parties)		7,100	7,300
AstraZeneca Agreements [Member] | China [Member] | Clinical and Development Milestone [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Potential milestone payments	15,000
AstraZeneca Agreements [Member] | China [Member] | Regulatory Milestone [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Potential milestone payments	$ 146,000
Direct Sales [Member] | Product Revenue, Net [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Total revenue		$ 11,894	$ 11,702	$ 12,070

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