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Collaboration Agreements, License Agreement and Revenues - Summary of Revenue Recognized Under the Collaboration Agreements - Additional Information 4 (Detail)	3 Months Ended
	Mar. 31, 2024 USD ($)
Europe [Member] | Astellas Agreement [Member]
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Changes in revenue from changes to estimated variable consideration	$ 0
Total Consideration	905,979,000
Europe [Member] | Astellas Agreement [Member] | License [Member]
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Total Consideration	618,975,000
U.S./RoW and China [Member]
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Changes in revenue from changes to estimated variable consideration	0
U.S./RoW and China [Member] | AstraZeneca Agreements [Member] | License [Member]
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Total Consideration	344,500,000
U.S./RoW and China [Member] | AstraZeneca Agreements [Member] | Co Development Information Sharing And Committee Services [Member]
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Total Consideration	625,600,000
U.S./RoW and China [Member] | AstraZeneca Agreements [Member] | China Performance Obligation [Member]
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Total Consideration	399,500,000
U.S./RoW and China [Member] | AstraZeneca Agreements [Member] | Product [Member]
Revenue Recognition, Multiple-deliverable Arrangements [Line Items]
Cumulative Revenue	$ 222,900,000

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- Definition

The total cash consideration received under a collaboration agreement that has been allocated to the different significant units of accounting and includes the portion that has been deferred for revenue recognition.

+ References

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- Definition

Total amount of revenue recognized for license and development services under the collaboration agreement as of a given date.

+ References

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- Definition

Amount of revenue recognized arising from contract liability from change in timeframe for performance obligation to be satisfied.

+ References

Reference 1: http://www.xbrl.org/2003/role/exampleRef
-Topic 606
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 10
-Subparagraph (e)
-Publisher FASB
-URI https://asc.fasb.org//1943274/2147479806/606-10-50-10

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