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Liability Related to Sale of Future Revenues - Additional Information (Detail) - USD ($) |  | 3 Months Ended | 6 Months Ended
--- | --- | --- | ---
Nov. 04, 2022 | Jun. 30, 2024 | Mar. 31, 2024 | Jun. 30, 2023 | Jun. 30, 2024 | Jun. 30, 2023
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Total revenue |  | $ 50,641,000 |  | $ 44,319,000 | $ 106,544,000 | $ 80,480,000
Interest expense related to sale of future revenues |  |  |  |  | 3,749,000 |
Interest paid |  |  | $ (5,700,000) |  | $ (5,653,000) |
NovaQuest Capital Management [Member] | Revenue Interest Financing Agreement [Member] |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Effective annual interest rate related to sale of future revenues |  |  |  |  | 15.63% |
NovaQuest Capital Management [Member] | Revenue Interest Financing Agreement [Member] | Minimum [Member] |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Prepayment amount of 2024 to 2030 | $ 80,000,000 |  |  |  |  |
NovaQuest Capital Management [Member] | Revenue Interest Financing Agreement [Member] | Maximum [Member] |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Prepayment amount of 2024 to 2030 | 125,000,000 |  |  |  |  |
NovaQuest Capital Management [Member] | Payment Period One [Member] | Revenue Interest Financing Agreement [Member] | Minimum [Member] |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Revenue interest payment | 62,500,000 |  |  |  |  |
NovaQuest Capital Management [Member] | Payment Cap Date on or before December 31, 2028 [Member] | Revenue Interest Financing Agreement [Member] |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Maximum payment cap amount | 100,000,000 |  |  |  |  |
NovaQuest Capital Management [Member] | Payment Cap Date on or after January 1, 2029 [Member] | Revenue Interest Financing Agreement [Member] |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Maximum payment cap amount | 112,500,000 |  |  |  |  |
NovaQuest Capital Management [Member] | Payment Cap Date after January 1, 2030 [Member] | Revenue Interest Financing Agreement [Member] |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Maximum payment cap amount | 125,000,000 |  |  |  |  |
NovaQuest Capital Management [Member] | Payment Period Two [Member] | Revenue Interest Financing Agreement [Member] | Minimum [Member] |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Revenue interest payment | 125,000,000 |  |  |  |  |
Product [Member] |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Total revenue |  | 49,643,000 |  | 23,889,000 | $ 80,181,000 | 48,049,000
Product [Member] | NovaQuest Capital Management [Member] | Revenue Interest Financing Agreement [Member] |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Revenue interest payment | 10,000,000 |  |  |  |  |
License [Member] |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Total revenue |  | 0 |  | 1,000,000 | 0 | 7,000,000
Other Revenue - Contract Manufacturing [Member] |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Total revenue |  | 269,000 |  | 5,158,000 | 1,147,000 | 9,050,000
Astellas Agreement [Member] |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Future revenue granted | $ 50,000,000 |  |  |  |  |
Percentage of revenue interest on global net sales | 100.00% |  |  |  |  |
Astellas Agreement [Member] | Maximum [Member] |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Revenue payment cap amount |  | 125,000,000 |  |  | 125,000,000 |
Astellas Agreement [Member] | Product [Member] |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Percentage of revenue sold | 22.50% |  |  |  |  |
Astellas Agreement [Member] | Milestone payments [Member] |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Percentage of revenue sold | 10.00% |  |  |  |  |
Astellas Agreement [Member] | Milestone payments [Member] | Payment Period One [Member] |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Percentage of revenue sold | 20.00% |  |  |  |  |
Development Revenue [Member] | Astellas Agreement [Member] |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Total revenue |  | 300,000 |  |  | 600,000 |
Drug Product Revenue [Member] |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Total revenue |  | 729,000 |  | 14,272,000 | 25,216,000 | 16,381,000
Drug Product Revenue [Member] | Astellas Agreement [Member] |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Total revenue |  | 700,000 |  |  | 500,000 |
Non-cash interest expense related to drug product revenue |  | $ 1,700,000 |  | $ 1,300,000 | $ 3,700,000 | $ 3,600,000

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