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Collaboration Agreements, License Agreement and Revenues - AstraZeneca U.S./RoW Agreement - Additional Information (Detail) - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended |
--- | --- | --- | ---
Jun. 30, 2024 | Mar. 31, 2024 | Jun. 30, 2023 | Jun. 30, 2024 | Jun. 30, 2023 | Dec. 31, 2023
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Accounts receivable from related parties | $ 6,412 |  |  | $ 6,412 |  | $ 12,553
Related cost of goods sold | $ 5,178 |  | $ 5,708 | $ 30,931 | $ 9,199 |
AstraZeneca U.S./RoW Agreement [Member] |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Cumulative catch-up net adjustment |  | $ 25,700 |  |  |  |
Related accounts receivable |  | 26,000 |  |  |  |
Related accrued liabilities |  | 11,500 |  |  |  |
Related cost of goods sold |  | $ 21,100 |  |  |  |

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