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Collaboration Agreements, License Agreement and Revenues - Drug Product Revenue - Additional Information (Detail) - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended | 12 Months Ended
--- | --- | --- | ---
Jun. 30, 2024 | Mar. 31, 2024 | Dec. 31, 2023 | Jun. 30, 2023 | Mar. 31, 2023 | Jun. 30, 2024 | Jun. 30, 2023 | Dec. 31, 2023
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Deferred Revenue | $ 9,546 |  | $ 12,740 |  |  | $ 9,546 |  | $ 12,740
Drug product revenue recognized | 50,641 |  |  | $ 44,319 |  | 106,544 | $ 80,480 |
Other long-term liabilities | 1,012 |  | 2,858 |  |  | 1,012 |  | 2,858
Astra Zeneca Agreements [Member] |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Royalty revenue recognized as drug product revenue |  |  |  |  |  | 73,118 |  |
Drug Product Revenue, Net [Member] |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Drug product revenue recognized | 729 |  |  | 14,272 |  | 25,216 | 16,381 |
Drug Product Revenue, Net [Member] | Astellas Agreement [Member] |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Drug product revenue recognized | 700 |  |  |  |  | 500 |  |
Drug Product Revenue, Net [Member] | Europe [Member] | Astellas Agreement [Member] |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Drug product revenue recognized | 1,095 |  |  | 463 |  | 2,116 | 840 |
Drug Product Revenue, Net [Member] | Europe [Member] | Astellas Europe Agreement [Member] |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Drug product revenue recognized |  |  |  |  |  | 5,400 |  |
Collaboration agreement payment |  |  |  |  |  | 35,300 |  |
Burdened manufacturing costs |  |  | 800 |  |  |  |  |
Drug Product Revenue, Net [Member] | Japan [Member] |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Drug product revenue recognized |  |  |  | 14,400 | $ 1,700 |  |  |
Drug Product Revenue, Net [Member] | Japan [Member] | Astellas Agreement [Member] |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Drug product revenue recognized | (366) |  |  | 13,809 |  | (2,571) | 15,541 |
Accrued liabilities | 2,200 |  | 1,200 |  |  | 2,200 |  | 1,200
Other long-term liabilities | 600 |  | 700 |  |  | 600 |  | 700
Drug Product Revenue, Net [Member] | API Shipment [Member] |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Drug product revenue recognized | 400 | $ 2,200 |  | 600 |  |  |  |
Bulk Drug Product [Member] | Astellas Europe Agreement [Member] |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Deferred Revenue |  |  | 17,700 |  |  |  |  | 17,700
Bulk Drug Product [Member] | Europe [Member] | Astellas Europe Agreement [Member] |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Drug product revenue recognized |  |  |  |  |  |  |  | 38,700
Accrued liabilities | 8,800 |  | $ 38,600 |  |  | 8,800 |  | $ 38,600
Bulk Drug Product [Member] | Europe [Member] | Astellas Europe Agreement [Member] | Royalty Revenue [Member] |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Royalty revenue recognized as drug product revenue | $ 1,100 |  |  | $ 500 |  | $ 2,100 | $ 800 |

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