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Collaboration Agreements, License Agreement and Revenues - Roll-forward of Related Contract Liabilities (Detail) $ in Thousands	9 Months Ended
	Sep. 30, 2024 USD ($)
AstraZeneca Agreements [Member]
Contract with Customer Liability [Line Items]
Balance at December 31, 2023	$ (179,851)
Additions	(82,185)
Recognized as Revenue	115,339
Currency Translation and Other	(270)
Balance at September 30, 2024	(146,967)
Drug Product Revenue, Net [Member] | Astellas Agreement [Member] | Europe [Member]
Contract with Customer Liability [Line Items]
Balance at December 31, 2023	(16,925)
Reclassified to Accrued Liability	5,605
Recognized as Revenue	3,210
Balance at September 30, 2024	$ (8,110)

X

- Definition

Contract with customer liability additions.

+ References

No definition available.

+ Details

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X

- Definition

Contract with customer, liability, increase (decrease) from current translation and other.

+ References

No definition available.

+ Details

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X

- Definition

Contract with customer liability.

+ References

No definition available.

+ Details

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X

- Definition

Contract with customer liability reclassified to accrued liability.

+ References

No definition available.

+ Details

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X

- Definition

Amount of obligation to transfer good or service to customer for which consideration has been received or is receivable.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 606
-SubTopic 10
-Name Accounting Standards Codification
-Section 45
-Paragraph 1
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479837/606-10-45-1

Reference 2: http://www.xbrl.org/2003/role/disclosureRef
-Topic 606
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 8
-Subparagraph (a)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479806/606-10-50-8

Reference 3: http://www.xbrl.org/2003/role/disclosureRef
-Topic 606
-SubTopic 10
-Name Accounting Standards Codification
-Section 45
-Paragraph 2
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479837/606-10-45-2

+ Details

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X

- Definition

Amount of revenue recognized that was previously included in balance of obligation to transfer good or service to customer for which consideration from customer has been received or is due.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 606
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 8
-Subparagraph (b)
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147479806/606-10-50-8

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