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Balance Sheet Components - Schedule of Accrued and Other Current Liabilities (Detail) - USD ($) $ in Thousands	Sep. 30, 2024	Dec. 31, 2023
Accrued Liabilities, Current [Abstract]
Preclinical and clinical trial accruals	$ 6,689	$ 27,663
API and bulk drug product price true-up	12,592	50,978
Litigation settlement	28,500	28,500
Payroll and related accruals	6,144	20,267
Accrued restructuring charge	14,173	3,697
Inventory cost related	8,521
Accrued co-promotion expenses - current	53,714	10,309
Roxadustat profit share to AstraZeneca		7,084
Lease termination related	4,558
Value added taxes and other taxes	7,121	6,615
Professional services	4,396	7,103
Current portion of liability related to sale of future revenues	332	5,654
Other	4,401	5,021
Total accrued and other current liabilities	$ 151,141	$ 172,891

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Accrued API and bulk drug product price true-up current.

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Accrued inventory cost.

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Total of the carrying values as of the balance sheet date of obligations incurred through that date and payable for obligations related to pre-clinical and clinical trial activities, including those performed by third parties. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).

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Accrued profit share current.

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Litigation settlement current.

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Carrying value as of the balance sheet date of obligations incurred and payable for real and property taxes. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).

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Carrying value as of the balance sheet date of obligations incurred and payable, pertaining to costs that are statutory in nature, are incurred on contractual obligations, or accumulate over time and for which invoices have not yet been received or will not be rendered. Examples include taxes, interest, rent and utilities. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).

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Carrying value as of the balance sheet date of obligations incurred through that date and payable for professional fees, such as for legal and accounting services received. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).

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Total of the carrying values as of the balance sheet date of obligations incurred through that date and payable for obligations related to services received from employees, such as accrued salaries and bonuses, payroll taxes and fringe benefits. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).

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