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Balance Sheet Components - Additional Information (Detail) - USD ($) | 1 Months Ended | 3 Months Ended | 12 Months Ended |
--- | --- | --- | --- | ---
Jul. 31, 2024 | Jun. 30, 2024 | Dec. 31, 2024 | Dec. 31, 2023 | Jul. 31, 2021
Schedule of Available-for-sale Securities [Line Items] |  |  |  |  |
Other-than-temporary impairment loss |  |  | $ 0 |  |
Litigation settlement receivable |  |  | 28,500,000 | $ 28,500,000 |
Depreciation expense for the continuing operations |  |  | 2,654,000 | 9,518,000 |
Depreciation expense for continuing operations |  |  | 1,200,000 | 7,000,000 |
API and bulk drug product price true-up |  |  | 13,071,000 | 50,978,000 |
Short-term investments |  |  | 0 | 121,898,000 |
Long-term investment |  |  | 0 |  |
Accrued litigation settlement |  |  | 28,500,000 | 28,500,000 |
Loss on disposal |  |  | 2,500,000 |  |
Restructuring plan, expected reduction to workforce, percentage | 75.00% |  |  |  |
Restructuring plan, non-recurring charges |  |  | 19,454,000 | 12,606,000 |
Cash payments for restructuring |  |  | 16,500,000 |  |
Accrued restructuring charges |  |  | 4,600,000 | $ 3,700,000 |
Eluminex Agreements [Member] |  |  |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |  |  |
Aggregate consideration received for milestone and upfront payments |  |  |  |  | $ 8,000,000
Astellas Agreement [Member] |  |  |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |  |  |
Payment to related parties |  | $ 35,300,000 |  |  |
AstraZeneca Agreements [Member] |  |  |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |  |  |
Payment to related parties |  | $ 11,500,000 |  |  |
Inventory write-down |  |  | $ 12,600,000 |  |

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