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v3.25.1

Collaboration Agreements, License Agreement and Revenues - Roll-forward of Related Contract Liabilities (Detail) $ in Thousands | 3 Months Ended
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Mar. 31, 2025 USD ($)
AstraZeneca Agreements [Member] |
Contract with Customer Liability [Line Items] |
Balance at December 31, 2024 | $ (132,097)
Additions | (35,363)
Recognized as Revenue (Discontinued Operations) | 36,863
Currency Translation and Other | (248)
Balance at March 31, 2025 | (130,845)
Drug Product Revenue, Net [Member] | Astellas Agreement [Member] | Europe [Member] |
Contract with Customer Liability [Line Items] |
Balance at December 31, 2024 | (9,901)
Recognized as Revenue | 814
Reclassified to Accrued Liability / Accounts Payable | 2,076
Balance at March 31, 2025 | $ (7,011)

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