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Collaboration Agreements, License Agreement and Revenues - Roll-forward of Related Contract Liabilities (Detail) $ in Thousands	9 Months Ended
	Sep. 30, 2025 USD ($)
AstraZeneca Agreements [Member]
Contract with Customer Liability [Line Items]
Balance at December 31, 2024	$ (132,097)
Additions	(82,494)
Recognized as Revenue (Discontinued Operations)	218,575
Currency Translation and Other	(3,984)
Balance at September 30, 2025	0
Drug Product Revenue, Net [Member] | Astellas Agreement [Member] | Europe [Member]
Contract with Customer Liability [Line Items]
Balance at December 31, 2024	(9,901)
Recognized as Revenue	3,321
Reclassified to Accrued Liability / Accounts Payable	903
Balance at September 30, 2025	$ (5,677)

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- Definition

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- Definition

Amount of obligation to transfer good or service to customer for which consideration has been received or is receivable.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Topic 606
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-Name Accounting Standards Codification
-Section 50
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Amount of revenue attributable to disposal group, including, but not limited to, discontinued operation.

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Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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