Effective Annual Interest Rate Related To Sale Of Future Revenues

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Future revenue granted.

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Interest paid related to sale of future revenues.

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Maximum payment cap amount.

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Non-cash interest expense related to drug product revenue

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Percentage of revenue interest on global net sales.

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Percentage of revenue sold.

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Prepayment amount.

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Revenue interest payment.

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Revenue payment cap amount.

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise.

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Liability Related to Sale of Future Revenues - Additional Information (Detail) - USD ($)	1 Months Ended	3 Months Ended		9 Months Ended
	Nov. 30, 2022	Sep. 30, 2025	Sep. 30, 2024	Sep. 30, 2025	Sep. 30, 2024
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Total revenue		$ 1,076,000	$ 123,000	$ 5,163,000	$ 26,486,000
Interest expense related to sale of future revenues				6,109,000
Interest paid				$ 450,000	5,700,000
NovaQuest Capital Management [Member] \| Revenue Interest Financing Agreement [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Effective annual interest rate related to sale of future revenues				15.23%
NovaQuest Capital Management [Member] \| Revenue Interest Financing Agreement [Member] \| Minimum [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Prepayment amount of 2024 to 2030	$ 80,000,000
NovaQuest Capital Management [Member] \| Revenue Interest Financing Agreement [Member] \| Maximum [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Prepayment amount of 2024 to 2030	125,000,000
NovaQuest Capital Management [Member] \| Payment Period One [Member] \| Revenue Interest Financing Agreement [Member] \| Minimum [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue interest payment	62,500,000
NovaQuest Capital Management [Member] \| Payment Cap Date on or before December 31, 2028 [Member] \| Revenue Interest Financing Agreement [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Maximum payment cap amount	100,000,000
NovaQuest Capital Management [Member] \| Payment Cap Date on or after January 1, 2029 [Member] \| Revenue Interest Financing Agreement [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Maximum payment cap amount	112,500,000
NovaQuest Capital Management [Member] \| Payment Cap Date after January 1, 2030 [Member] \| Revenue Interest Financing Agreement [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Maximum payment cap amount	125,000,000
NovaQuest Capital Management [Member] \| Payment Period Two [Member] \| Revenue Interest Financing Agreement [Member] \| Minimum [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue interest payment	125,000,000
Product [Member] \| NovaQuest Capital Management [Member] \| Revenue Interest Financing Agreement [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue interest payment	10,000,000
Other Revenue - Contract Manufacturing [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Total revenue		119,000	385,000	$ 396,000	1,532,000
Astellas Agreement [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Future revenue granted	$ 50,000,000
Percentage of revenue interest on global net sales	100.00%
Astellas Agreement [Member] \| Maximum [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue payment cap amount		125,000,000		125,000,000
Astellas Agreement [Member] \| Product [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Percentage of revenue sold	22.50%
Astellas Agreement [Member] \| Milestone payments [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Percentage of revenue sold	10.00%
Astellas Agreement [Member] \| Milestone payments [Member] \| Payment Period One [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Percentage of revenue sold	20.00%
Development Revenue [Member] \| Astellas Agreement [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Total revenue		100,000	400,000	400,000	1,000,000
Drug Product Revenue [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Total revenue		957,000	(262,000)	4,767,000	24,954,000
Drug Product Revenue [Member] \| Astellas Agreement [Member]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Total revenue		1,000,000	(300,000)	4,800,000	(700,000)
Non-cash interest expense related to drug product revenue		$ 2,000,000	$ 2,000,000	$ 6,100,000	$ 5,800,000