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Stockholders' Equity - Schedule of Common Stock Reserved for Future Issuance (Details) - shares | Mar. 31, 2022 | Dec. 31, 2021
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Class Of Stock [Line Items] |  |  |
Common stock, reserved for future issuance |  | 3,108,000 | 2,739,000
Stock Option Awards Issued and Outstanding |  |  |
Class Of Stock [Line Items] |  |  |
Common stock, reserved for future issuance |  | 2,175,000 | 2,000,000
Authorized for Grants under the 2016 Equity Incentive Plan |  |  |
Class Of Stock [Line Items] |  |  |
Common stock, reserved for future issuance | [1] | 491,000 | 332,000
Authorized for grants under the 2016 Employee Stock Purchase Plan |  |  |
Class Of Stock [Line Items] |  |  |
Common stock, reserved for future issuance | [2] | 395,000 | 326,000
Authorized for Grants under the Inducement Plan |  |  |
Class Of Stock [Line Items] |  |  |
Common stock, reserved for future issuance | [3] | 47,000 | 81,000
[1] | On January 1, 2022, th e number of authorized shares in the 2016 Plan increased by 404,000 shares pursuant to the evergreen provisions of the 2016 Plan.
[2] | On January 1, 2022, the number of authorized shares in the 2016 Employee Stock Purchase Plan increased by 100,000 sh ares pursuant to the evergreen provisions of the 2016 Employee Stock Purchase Plan.
[3] | O n February 5, 2021, 300,000 sh ares were authorized pursuant to the terms of the Inducement Plan; 38,000 shares were issued under the Inducement Plan during the three months ended March 31, 2022.

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- Definition Aggregate number of common shares reserved for future issuance. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02.29) -URI http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682 + Details
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