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Collaboration Agreements - Additional Information (Detail) - USD ($) |  |  |  | 1 Months Ended | 3 Months Ended | 9 Months Ended | 12 Months Ended |  |
--- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Feb. 28, 2023 | May 31, 2022 | Dec. 11, 2020 | Aug. 31, 2017 | Sep. 30, 2023 | Sep. 30, 2022 | Sep. 30, 2023 | Sep. 30, 2022 | Dec. 31, 2020 | Dec. 31, 2022 | Jan. 14, 2021
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Loss from G42 Promissory Note early redemption |  |  |  |  |  |  | $ 313,000 | $ 0 |  |  |
Contract liabilities, net of current portion |  |  |  |  | $ 18,669,000 |  | 18,669,000 |  |  | $ 18,669,000 |
Revenue |  |  |  |  | 0 | $ 0 | 0 | 2,009,000 |  |  |
G42 Investments |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Shares sold (in shares) |  | 10,386,274 |  |  |  |  |  |  |  |  |
Sale of stock, price per share (in usd per shares) |  | $ 2.41 |  |  |  |  |  |  |  |  |
Sale of stock, consideration received on transaction, gross |  | $ 25,000,000 |  |  |  |  |  |  |  |  |
Sale of stock, consideration received on transaction |  | 12,500,000 |  |  |  |  |  |  |  |  |
Accounts and financing receivable, after allowance for credit loss |  | 12,500,000 |  |  |  |  |  |  |  |  |
Proceeds from collection of notes receivable | $ 12,000,000 |  |  |  |  |  |  |  |  |  |
Discount rate | 3.75% |  |  |  |  |  |  |  |  |  |
Loss from G42 Promissory Note early redemption | $ 300,000 |  |  |  |  |  |  |  |  |  |
G2 Investments Purchase Agreement And Cogna Collaborative And License Agreement | G42 Investments |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Sale of stock, consideration received on transaction, gross |  | 25,000,000 |  |  |  |  |  |  |  |  |
Accounts and financing receivable, after allowance for credit loss |  | 12,500,000 |  |  |  |  |  |  |  |  |
Proceeds from collection of notes receivable | $ 12,000,000 |  |  |  |  |  |  |  |  |  |
Discount rate | 3.75% |  |  |  |  |  |  |  |  |  |
Loss from G42 Promissory Note early redemption | $ 300,000 |  |  |  |  |  |  |  |  |  |
Collaborative arrangement, contingent consideration |  | 30,000,000 |  |  |  |  |  |  |  |  |
Collaborate arrangement, contingent consideration transferred, cash |  | 30,000,000 |  |  |  |  |  |  |  |  |
Contract liabilities, net of current portion |  |  |  |  | 18,700,000 |  | 18,700,000 |  |  |  |
Discount on note receivable |  |  |  |  |  |  | 600,000 |  |  |  |
Collaboration revenue recognized |  |  |  |  | 0 |  | 0 |  |  |  |
Revenue |  |  |  |  | 0 |  | 0 |  |  |  |
Receivables, fair value disclosure |  |  |  |  | 11,900,000 |  | 11,900,000 |  |  |  |
G2 Investments Purchase Agreement And Cogna Collaborative And License Agreement | G42 Investments | Class A Common Stock |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Common stock, value |  | $ 5,700,000 |  |  |  |  |  |  |  |  |
Share price (in usd per share) |  | $ 0.55 |  |  |  |  |  |  |  |  |
G2 Investments Purchase Agreement And Cogna Collaborative And License Agreement | Cogna |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Royalties receivable, period |  | 10 years |  |  |  |  |  |  |  |  |
Collaborative Arrangements | JDRF |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Maximum funding percentage of research and development milestones |  |  |  | 50.00% |  |  |  |  |  |  |
Collaborative Arrangements | JDRF | Phase 2 MRCT | License and Technology Transfer Services of Chemistry and Manufacturing Know-How |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Adjustments to transaction price for performance obligations |  |  |  |  |  |  | 0 | 0 |  |  |
Collaborative Arrangements | Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. | Phase 2 MRCT |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Maximum contribution amount to clinical trial |  |  |  |  |  |  |  |  |  |  | $ 3,000,000
Potential development and regulatory milestone payments |  |  |  |  |  |  |  |  |  |  | $ 3,000,000
Collaborative Arrangements | Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. | Phase 2 MRCT | License and Technology Transfer Services of Chemistry and Manufacturing Know-How |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Adjustments to transaction price for performance obligations |  |  |  |  |  |  | 0 | 2,000,000 |  |  |
Collaborative Arrangements | Anteris Bio Inc |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Potential development and regulatory milestone payments |  |  | $ 151,000,000 |  |  |  |  |  |  |  |
License Fee Received |  |  | $ 2,000,000 |  |  |  |  |  |  |  |
Contract with customer, liability, revenue recognized |  |  |  |  | $ 0 | $ 0 | $ 0 | $ 0 |  |  |
Collaborative Arrangements | Anteris Bio Inc | License and Technology Transfer Services of Chemistry and Manufacturing Know-How |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
License Fee Received |  |  |  |  |  |  |  |  | $ 2,000,000 |  |
Equity interest received |  |  |  |  |  |  |  |  | $ 4,200,000 |  |

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