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Commitments and Contingencies - Additional Information (Detail) - Novo License Agreement - USD ($) $ in Millions | Dec. 31, 2021 | Feb. 28, 2007
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Developmental and Regulatory Milestone Payment | Type 1 Diabetes |  |
Commitments And Contingencies [Line Items] |  |
Potential milestone payment |  | $ 9.0
Developmental and Regulatory Milestone Payment | Type 2 Diabetes | Maximum |  |
Commitments And Contingencies [Line Items] |  |
Potential milestone payment |  | 50.5
Developmental and Regulatory Milestone Payment | Other Indication | Maximum |  |
Commitments And Contingencies [Line Items] |  |
Potential milestone payment |  | 115.0
Sales-based Milestones Payment |  |
Commitments And Contingencies [Line Items] |  |
Potential milestone payment |  | $ 75.0
Satisfaction of Milestone Payment |  |
Commitments And Contingencies [Line Items] |  |
Potential milestone payment | $ 2.0 |

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