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Share-Based Compensation (Tables)
9 Months Ended
Sep. 30, 2023
Share-Based Payment Arrangement [Abstract]  
Summary of Stock Award Activity for the Period
The following table summarizes the activity related to the stock option awards for the nine months ended September 30, 2023:
Number of Shares Weighted
Average Exercise Price
Awards outstanding at December 31, 20228,418,571 $2.17 
Granted1,176,868 0.87 
Forfeited(50,000)1.29 
Awards outstanding at September 30, 20239,545,439 $2.01 
Options exercisable at September 30, 20235,018,072 $3.04 
Weighted average remaining contractual term6.6 Years
Options vested and expected to vest at September 30, 20238,188,444 $2.21 
Weighted average remaining contractual term7.5 Years
Summary of Compensation Expense Related to Grants of Stock Options
Compensation expense related to the grants of stock options is included in research and development and general and administrative expense as follows (in thousands):
Three Months Ended September 30,Nine Months Ended September 30,
2023202220232022
Research and development$113 $109 $316 $289 
General and administrative320 229 859 692 
Total share-based compensation expense$433 $338 $1,175 $981