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Collaboration Agreements - Additional Information (Detail) - USD ($)				1 Months Ended	3 Months Ended		9 Months Ended		12 Months Ended
	Feb. 28, 2023	May 31, 2022	Dec. 11, 2020	Aug. 31, 2017	Sep. 30, 2023	Sep. 30, 2022	Sep. 30, 2023	Sep. 30, 2022	Dec. 31, 2020	Dec. 31, 2022	Jan. 14, 2021
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Loss from G42 Promissory Note early redemption							$ 313,000	$ 0
Contract liabilities, net of current portion					$ 18,669,000		18,669,000			$ 18,669,000
Revenue					0	$ 0	0	2,009,000
G42 Investments
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Shares sold (in shares)		10,386,274
Sale of stock, price per share (in usd per shares)		$ 2.41
Sale of stock, consideration received on transaction, gross		$ 25,000,000
Sale of stock, consideration received on transaction		12,500,000
Accounts and financing receivable, after allowance for credit loss		12,500,000
Proceeds from collection of notes receivable	$ 12,000,000
Discount rate	3.75%
Loss from G42 Promissory Note early redemption	$ 300,000
G2 Investments Purchase Agreement And Cogna Collaborative And License Agreement | G42 Investments
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Sale of stock, consideration received on transaction, gross		25,000,000
Accounts and financing receivable, after allowance for credit loss		12,500,000
Proceeds from collection of notes receivable	$ 12,000,000
Discount rate	3.75%
Loss from G42 Promissory Note early redemption	$ 300,000
Collaborative arrangement, contingent consideration		30,000,000
Collaborate arrangement, contingent consideration transferred, cash		30,000,000
Contract liabilities, net of current portion					18,700,000		18,700,000
Discount on note receivable							600,000
Collaboration revenue recognized					0		0
Revenue					0		0
Receivables, fair value disclosure					11,900,000		11,900,000
G2 Investments Purchase Agreement And Cogna Collaborative And License Agreement | G42 Investments | Class A Common Stock
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Common stock, value		$ 5,700,000
Share price (in usd per share)		$ 0.55
G2 Investments Purchase Agreement And Cogna Collaborative And License Agreement | Cogna
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Royalties receivable, period		10 years
Collaborative Arrangements | JDRF
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Maximum funding percentage of research and development milestones				50.00%
Collaborative Arrangements | JDRF | Phase 2 MRCT | License and Technology Transfer Services of Chemistry and Manufacturing Know-How
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Adjustments to transaction price for performance obligations							0	0
Collaborative Arrangements | Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. | Phase 2 MRCT
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Maximum contribution amount to clinical trial											$ 3,000,000
Potential development and regulatory milestone payments											$ 3,000,000
Collaborative Arrangements | Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. | Phase 2 MRCT | License and Technology Transfer Services of Chemistry and Manufacturing Know-How
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Adjustments to transaction price for performance obligations							0	2,000,000
Collaborative Arrangements | Anteris Bio Inc
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Potential development and regulatory milestone payments			$ 151,000,000
License Fee Received			$ 2,000,000
Contract with customer, liability, revenue recognized					$ 0	$ 0	$ 0	$ 0
Collaborative Arrangements | Anteris Bio Inc | License and Technology Transfer Services of Chemistry and Manufacturing Know-How
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
License Fee Received									$ 2,000,000
Equity interest received									$ 4,200,000

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