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Commitments and Contingencies - Additional Information (Detail) - Novo License Agreement - USD ($) $ in Millions	Dec. 31, 2021	Feb. 28, 2007
Developmental and Regulatory Milestone Payment | Type 1 Diabetes
Commitments And Contingencies [Line Items]
Potential milestone payment		$ 9.0
Developmental and Regulatory Milestone Payment | Type 2 Diabetes | Maximum
Commitments And Contingencies [Line Items]
Potential milestone payment		50.5
Developmental and Regulatory Milestone Payment | Other Indication | Maximum
Commitments And Contingencies [Line Items]
Potential milestone payment		115.0
Sales-based Milestones Payment
Commitments And Contingencies [Line Items]
Potential milestone payment		$ 75.0
Satisfaction of Milestone Payment
Commitments And Contingencies [Line Items]
Potential milestone payment	$ 2.0

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