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Segment Information (Tables)
 6 Months Ended
Jun. 30, 2026
Segment Reporting [Abstract]  
Schedule of Segment Reporting Information, by Segment
Significant segment expenses are included in the table below and represent direct and indirect research and development expenses by project for the three and six months ended June 30, 2026, and 2025 were as follows (in thousands):
Three Months Ended June 30,Six months ended June 30,
2026202520262025
Direct research and development expense:
Cadisegliatin5,488 1,992 11,995 2,910 
Other projects*
240 136 317 249 
Indirect research and development expense†3,042 1,975 5,436 3,774 
Total research and development expense$8,770 $4,103 $17,748 $6,933 
*
Includes HPP737 and azeliragon
†
Includes share-based compensation