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Income Taxes - Schedule of effective income tax rate reconciliation (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Income Tax Disclosure [Abstract]    
Income tax benefit computed at federal statutory tax rate $ (9,445) $ (7,687)
Change in valuation allowance 13,045 8,717
Return to provision adjustments 0 (745)
General business credits (3,108) (1,114)
Other permanent differences 0 119
Stock compensation (1,923) 0
Section 162(m) limitation 809 0
Change in uncertain tax position 622 223
Other 0 487
Income tax benefit $ 0 $ 0