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CONDENSED STATEMENTS OF CASH FLOWS - USD ($)
 6 Months Ended
Jun. 30, 2023
Jun. 30, 2022
Cash flows from operating activities:    
Net loss $ (42,070,000) $ (51,899,000)
Adjustments to reconcile net loss to net cash used in operations:    
Stock-based compensation 3,535,000 3,046,000
Depreciation 2,041,000 1,134,000
Non-cash operating lease expense 175,000 141,000
Net amortization (accretion) of investments (504,000) 1,396,000
Impairment loss 0 400,000
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets 4,027,000 4,285,000
Other assets 89,000 13,000
Accounts payable (5,174,000) (4,522,000)
Accrued expenses and other current liabilities (7,555,000) 3,539,000
Non-current operating lease liabilities (384,000) (337,000)
Deferred revenue 743,000 211,000
Net cash used in operating activities (45,077,000) (42,593,000)
Cash flows from investing activities:    
Purchases of property and equipment (371,000) (10,171,000)
Net change in investments 69,929,000 (1,778,000)
Net cash provided by (used in) investing activities 69,558,000 (11,949,000)
Cash flows from financing activities:    
Proceeds from the exercises of stock options and purchases pursuant to employee stock purchase plan 72,000 144,000
Taxes paid related to net share settlement of equity awards (39,000) 0
Net cash provided by financing activities 33,000 144,000
Net increase (decrease) in cash and cash equivalents 24,514,000 (54,398,000)
Cash and cash equivalents, beginning of period 47,379,000 92,268,000
Cash and cash equivalents, end of period 71,893,000 37,870,000
Supplemental disclosures of non-cash financial activities:    
Unpaid amounts related to purchases of property and equipment 15,000 184,000
Operating lease liabilities recognized for operating right-of-use assets 0 5,447,000
Operating right-of-use assets exchanged for operating lease liabilities $ 0 $ 2,945,000