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Segment Reporting (Tables) | 3 Months Ended
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Mar. 31, 2026
Segment Reporting [Abstract] |
Schedule of Segment Reporting Information, by Segment | The following table sets forth information about the Company’s single reportable segment and the significant expenses reviewed by the CODM, including a reconciliation to net loss (in thousands):
| Three Months Ended March 31,
| 2026 |  | 2025
Revenue | $ | — |  |  | $ | — |
Operating expenses: |  |  |
Research and development: |  |  |
SL-325 1 | 2,861 |  |  | 2,229 |
Other research and development 2,3 | 4,667 |  |  | 4,606 |
Research and development non-equity compensation | 2,382 |  |  | 2,397 |
Research and development equity compensation | 1,036 |  |  | 687 |
Total research and development | 10,946 |  |  | 9,919 |
General and administrative expenses: |  |  |
General and administrative non-equity compensation | 1,427 |  |  | 1,353 |
General and administrative equity compensation | 1,379 |  |  | 1,033 |
Other general and administrative including legal and accounting fees, facilities, insurance, travel and depreciation | 1,793 |  |  | 2,084 |
Total general and administrative | 4,599 |  |  | 4,470 |
Expense from operations | 15,545 |  |  | 14,389 |
Loss from operations | (15,545) |  |  | (14,389) |
Other Income | 778 |  | 687 |
Net Loss | $ | (14,767) |  |  | $ | (13,702) |
1 Expenses for SL-325 that were incurred prior to it being nominated a product candidate are included in “other research and development”. 2 Other research and development expense includes technical operations expense of $1.9 million and $2.4 million, research activities for other pipeline compounds and facility expenses of $1.9 million and $1.3 million and depreciation expense of $0.9 million and $0.9 million for the three months ended March 31, 2026 and 2025, respectively. 3 Other research and development expense includes a gain of $0.7 million due to a change in estimate and expense of $2.0 million for the three months ended March 31, 2026 and 2025, respectively, related to SL-172154 which was discontinued in October 2024.

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- Definition Tabular disclosure of the profit or loss and total assets for each reportable segment. An entity discloses certain information on each reportable segment if the amounts (a) are included in the measure of segment profit or loss reviewed by the chief operating decision maker or (b) are otherwise regularly provided to the chief operating decision maker, even if not included in that measure of segment profit or loss. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 25 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-25 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 22 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-22 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 30 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-30 + Details
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