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Revenues (Narrative) (Details) - USD ($) | 12 Months Ended
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Dec. 31, 2015 | Dec. 31, 2014 | Dec. 31, 2013
Product Revenues |  |  |
Net product revenue | $ 33,013,184 | $ 36,683,762 | $ 31,100,698
Accrued liabilities, current | 9,534,268 | 10,506,769 |
Other Revenues |  |  |
Other revenue, upfront payment | 1,400,000 |  |
Other revenue, potential upfront payments related to regulatory approval | 1,700,000 |  |
Other revenue, potential upfront payment related to product sales | 4,700,000 |  |
Cumulative upfront payment | 1,500,000 |  |
Product Sales Related Accruals - Rebates, Product Returns, Administrative Fees and Service Fees |  |  |
Product Revenues |  |  |
Accrued liabilities, current | 6,800,000 | 5,200,000 |
Product, Caldolor |  |  |
Product Revenues |  |  |
Net product revenue | 3,112,128 | 2,721,346 | 2,089,655
Product, Acetadote, Generic |  |  |
Product Revenues |  |  |
Net product revenue | 4,500,000 | 5,800,000 | 9,200,000
Product Sales Related Allowances - Chargebacks, Cash Discounts and Damaged Goods |  |  |
Product Revenues |  |  |
Accounts receivable, allowances, current | 400,000 | 400,000 |
Collaborative Arrangement, Federal Small Business Grant Programs |  |  |
Other Revenues |  |  |
Other revenues, grants | 200,000 | 100,000 | $ 100,000
Outside US | Product, Caldolor |  |  |
Product Revenues |  |  |
Net product revenue | $ 800,000 | $ 500,000 |

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