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Income Taxes (Details Textual) - USD ($)
 3 Months Ended
Mar. 31, 2017
Jan. 01, 2017
Dec. 31, 2016
Operating Loss Carryforwards [Line Items]      
Operating loss carryforwards $ 44,100,000    
Cumulative effect from change in accounting principal   $ 1,082,924  
Deferred tax assets, net 3,537,483   $ 3,119,930
Income tax windfall benefit 100,000    
State and Local Jurisdiction      
Operating Loss Carryforwards [Line Items]      
Operating loss carryforwards $ 45,400,000    
Restricted Stock      
Operating Loss Carryforwards [Line Items]      
Share-based payment award, vested in period (in shares) 146,275    
Accounting Standards Update 2016-09      
Operating Loss Carryforwards [Line Items]      
Deferred tax assets, net   1,100,000  
Accounting Standards Update 2016-09 | Retained earnings      
Operating Loss Carryforwards [Line Items]      
Cumulative effect from change in accounting principal   $ 1,100,000  
Orphan Drug and Research and Development Tax Credit      
Operating Loss Carryforwards [Line Items]      
Valuation allowance $ 1,000,000