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Intangible Assets (Tables)
 12 Months Ended
Dec. 31, 2017
Goodwill and Intangible Assets Disclosure [Abstract]  
Schedule of intangible assets
Intangible assets consisted of the following at December 31:
 
 
2017
 
2016
 
 
 
 
 
Product and license rights
 
$
21,879,981

 
$
20,543,262

Less: accumulated amortization
 
(6,564,007
)
 
(4,988,333
)
Total product and license rights
 
15,315,974

 
15,554,929

Patents
 
9,177,647

 
8,844,994

Less: accumulated amortization
 
(3,158,990
)
 
(2,298,442
)
Total patents
 
6,018,657

 
6,546,552

Trademarks
 
118,934

 
61,715

Less: accumulated amortization
 
(9,020
)
 
(9,020
)
Total trademarks
 
109,914

 
52,695

Total intangible assets
 
$
21,444,545

 
$
22,154,176
Schedule of expected amortization expense of intangible assets
The expected amortization expense for the Company's current balance of intangible assets are as follows:
Year ending December 31:
 
 
2018
 
$
2,519,024

2019
 
2,542,770

2020
 
2,614,010

2021
 
2,465,544

2022 and thereafter
 
11,303,197

 
 
$
21,444,545