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Consolidated Statements of Income and Comprehensive Income (Loss) - USD ($)
 12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Revenues:      
Net product revenue $ 40,376,563 $ 32,478,185 $ 33,013,184
Other revenue 773,568 547,375 505,867
Net revenues 41,150,131 33,025,560 33,519,051
Costs and expenses:      
Cost of products sold 7,370,585 5,958,660 4,968,170
Selling and marketing 21,492,937 14,553,481 13,994,768
Research and development 3,901,365 3,190,700 3,847,651
General and administrative 10,030,370 8,561,811 7,607,588
Amortization 2,436,222 2,194,039 1,989,264
Total costs and expenses 45,231,479 34,458,691 32,407,441
Operating income (loss) (4,081,348) (1,433,131) 1,111,610
Interest income 299,326 204,661 209,183
Interest expense (92,904) (106,392) (73,856)
Income (loss) before income taxes (3,874,926) (1,334,862) 1,246,937
Income tax (expense) benefit (4,174,889) 330,924 (575,829)
Net income (loss) (8,049,815) (1,003,938) 671,108
Net loss at subsidiary attributable to noncontrolling interests 71,182 59,255 60,243
Net income (loss) attributable to common shareholders $ (7,978,633) $ (944,683) $ 731,351
Earnings (loss) per share attributable to common shareholders:      
Basic (in USD per share) $ (0.50) $ (0.06) $ 0.04
Diluted (in USD per share) $ (0.50) $ (0.06) $ 0.04
Weighted-average common shares outstanding:      
Basic (in shares) 15,911,577 16,236,525 16,715,970
Diluted (in shares) 15,911,577 16,236,525 17,094,754
Comprehensive income (loss) attributable to common shareholders $ (7,978,633) $ (944,683) $ 731,351
Net loss at subsidiary attributable to noncontrolling interests 71,182 59,255 60,243
Total comprehensive income (loss) $ (8,049,815) $ (1,003,938) $ 671,108