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Omeclamox®-Pak, Ethyol®, RediTrex®, Totect® and Vibativ® - Narrative (Details) - USD ($) shares in Thousands |  | 1 Months Ended | 12 Months Ended
--- | --- | --- | ---
Oct. 29, 2013 | Nov. 30, 2016 | Dec. 31, 2018 | Dec. 31, 2017 | Dec. 31, 2016
Business Acquisition [Line Items] |  |  |  |  |
Payments for asset acquisitions |  |  | $ 2,300,000 |  |
Revenue from Contract with Customer, Excluding Assessed Tax |  |  | 40,200,832 | $ 40,376,563 | $ 32,478,185
Other revenue, potential upfront payment related to product sales |  |  | 4,600,000 |  |
Payments to acquire businesses |  |  | 20,000,000 | 0 | 0
Amended International Agreement | Pernix Therapeutics |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |
Other revenue, potential upfront payment related to product sales | $ 4,000,000.0 |  | 2,300,000 |  |
Omeclamox-Pak |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |
Revenue from Contract with Customer, Excluding Assessed Tax |  |  | 600,000 | 1,800,000 |
Ethyol | Minimum |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |
Royalty payments based on percentage over gross profits | 30.00% |  |  |  |
Ethyol | Maximum |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |
Royalty payments based on percentage over gross profits | 50.00% |  |  |  |
Methotrexate |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |
Payments to acquire businesses |  | $ 100,000 |  |  |
Liabilities incurred |  | $ 900,000 |  |  |
Stock issued during period, acquisitions |  |  | 1,100,000 | 1,300,000 |
Omeclamox-Pak |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |
Revenue from Contract with Customer, Excluding Assessed Tax |  |  | 623,297 | 1,761,868 | 2,536,027
Ethyol |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |
Revenue from Contract with Customer, Excluding Assessed Tax |  |  | $ 10,545,906 | $ 10,835,038 | $ 838,386
Restricted Stock | Methotrexate |  |  |  |  |
Business Acquisition [Line Items] |  |  |  |  |
Stock issued during period, acquisitions (in shares) |  | 180 |  |  |

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