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Commitments and Contingencies (Details) - Collaborative Arrangement, Transaction with Party to Collaborative Arrangement - USD ($)
$ in Thousands
Feb. 02, 2022
Dec. 31, 2021
Kyowa Kirin    
Other Commitments [Line Items]    
Upfront payment   $ 13,500
Milestone payments, maximum   $ 3,500
Collaborative arrangement, term   10 years
Kyowa Kirin | Minimum    
Other Commitments [Line Items]    
Tiered royalty, percent   5.00%
Kyowa Kirin | Maximum    
Other Commitments [Line Items]    
Tiered royalty, percent   10.00%
Melinta Therapeutics, LLC and Targanta Therapeutics Corporation | Within 30 Days Of First sNDA Filing    
Other Commitments [Line Items]    
Sales milestone payments, receivable   $ 500
Melinta Therapeutics, LLC and Targanta Therapeutics Corporation | Following Approval Of First sNDA    
Other Commitments [Line Items]    
Sales milestone payments, receivable   $ 500
Melinta Therapeutics, LLC and Targanta Therapeutics Corporation | Subsequent Event    
Other Commitments [Line Items]    
Sales milestone payments, receivable $ 1,000  
Gain contingency, unrecorded amount $ 1,000