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Commitments and Contingencies (Details) - Collaborative Arrangement, Transaction with Party to Collaborative Arrangement - USD ($)
$ in Thousands
Dec. 31, 2022
Nov. 07, 2022
Feb. 02, 2022
Jan. 03, 2022
Kyowa Kirin        
Other Commitments [Line Items]        
Milestone payments, maximum $ 3,500     $ 3,500
Collaborative arrangement, term 10 years      
Kyowa Kirin | Minimum        
Other Commitments [Line Items]        
Tiered royalty, percent 5.00%      
Kyowa Kirin | Maximum        
Other Commitments [Line Items]        
Tiered royalty, percent 10.00%     10.00%
Melinta Therapeutics, LLC and Targanta Therapeutics Corporation        
Other Commitments [Line Items]        
Sales milestone payments, receivable   $ 1,000    
Gain contingency, unrecorded amount   $ 1,000    
Melinta Therapeutics, LLC and Targanta Therapeutics Corporation | Within 30 Days Of First sNDA Filing        
Other Commitments [Line Items]        
Sales milestone payments, receivable     $ 500  
Melinta Therapeutics, LLC and Targanta Therapeutics Corporation | Following Approval Of First sNDA        
Other Commitments [Line Items]        
Sales milestone payments, receivable     $ 500