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Condensed Consolidated Statements of Operations and Comprehensive Loss (USD $)
In Thousands, except Per Share data, unless otherwise specified
 3 Months Ended 6 Months Ended 27 Months Ended
Jun. 30, 2013
Jun. 30, 2012
Jun. 30, 2013
Jun. 30, 2012
Jun. 30, 2013
Operating expenses:          
Research and development $ 2,576 $ 1,351 $ 5,256 $ 2,297 $ 12,749
General and administrative 3,445 1,883 5,940 3,903 14,600
Total operating expenses 6,021 3,234 11,196 6,200 27,349
Loss from operations (6,021) (3,234) (11,196) (6,200) (27,349)
Interest income 25   43   62
Net loss (5,996) (3,234) (11,153) (6,200) (27,287)
Accretion of convertible preferred stock to redemption value         (101)
Net loss applicable to common stockholders (5,996) (3,234) (11,153) (6,200) (27,388)
Net loss per share applicable to common stockholders-basic and diluted (in dollars per share) $ (0.36) $ (2.09) $ (0.74) $ (4.22) $ (4.35)
Weighted average number of common shares used in net loss per share applicable to common stockholders-basic and diluted (in shares) 16,869 1,548 15,132 1,469 6,302
Net loss (5,996) (3,234) (11,153) (6,200) (27,287)
Other comprehensive loss          
Unrealized losses on available-for-sale securities (27)   (20)   (26)
Comprehensive loss (6,023) (3,234) (11,173) (6,200) (27,313)
Non-cash stock-based compensation expenses included in operating expenses are as follows:          
Stock-based compensation expense     2,211 559 3,939
Research and development
          
Non-cash stock-based compensation expenses included in operating expenses are as follows:          
Stock-based compensation expense 609 256 1,035 493 2,447
General and administrative
          
Non-cash stock-based compensation expenses included in operating expenses are as follows:          
Stock-based compensation expense $ 765 $ 43 $ 1,176 $ 113 $ 1,492