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Condensed Consolidated Statements of Cash Flows (USD $)
In Thousands, unless otherwise specified
 6 Months Ended 27 Months Ended
Jun. 30, 2013
Jun. 30, 2012
Jun. 30, 2013
Cash flows from operating activities:      
Net loss $ (11,153) $ (6,200) $ (27,287)
Adjustments to reconcile net loss to net cash used in operating activities:      
Depreciation and amortization 100 22 193
Accretion of discount (amortization of premium) on debt securities 226   303
Stock-based compensation expense 2,211 559 3,939
Changes in operating assets and liabilities:      
Prepaid expenses and other assets (338) (165) (912)
Accounts payable (659) 328 216
Accrued expenses and other non-current liabilities 393 720 1,612
Net cash used in operating activities (9,220) (4,736) (21,936)
Cash flows from investing activities:      
Purchases of property, plant and equipment (234) (456) (1,083)
Sales and maturities of short-term investments 1,000   1,000
Purchases of short-term investments (10,783)   (27,481)
Increase in restricted cash   (93) (93)
Net cash used in investing activities (10,017) (549) (27,657)
Cash flows from financing activities:      
Proceeds from issuance of preferred stock, net of issuance costs   34,992 41,091
Increase in deferred financing costs   (182)  
Net proceeds from the issuance of common stock 32,654 1 36,695
Net cash provided by financing activities 32,654 34,811 77,786
Net increase in cash and cash equivalents 13,417 29,526 28,193
Cash and cash equivalents at beginning of period 14,776 4,541  
Cash and cash equivalents at end of period 28,193 34,067 28,193
Supplemental disclosure of non-cash financing activity      
Accretion of convertible preferred stock to redemption value     (101)
Conversion of convertible preferred stock to common stock     $ 41,192