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Income Taxes - Components of Deferred Tax Assets (Details) - USD ($) $ in Thousands | Dec. 31, 2017 | Dec. 31, 2016
--- | --- | ---
Deferred Tax Assets: |  |
Net operating loss carryforwards | $ 53,228 | $ 53,654
Tax credit carryforwards | 3,944 | 3,034
Accrued expenses | 687 | 1,737
Stock based compensation | 4,591 | 7,750
Intangibles | 2,240 | 3,366
Other | 903 | 1,181
Gross deferred tax assets | 65,593 | 70,722
Valuation allowance | (65,593) | (70,722)
Net deferred tax assets | $ 0 | $ 0

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