XML 73 R41.htm IDEA: XBRL DOCUMENT v3.10.0.1
Consolidated Statements of Operations and Comprehensive Loss - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Income Statement [Abstract]      
Revenues $ 295 $ 653 $ 277
Costs and expenses:      
Costs of revenues 790 5,401 2,249
Research and development 18,337 21,641 18,433
Selling, general and administrative 27,744 49,223 51,594
Restructuring 4,030 5,400 0
Total costs and expenses 50,901 81,665 72,276
Loss from operations (50,606) (81,012) (71,999)
Interest income, net 752 659 436
Other expense, net (36) (164) (20)
Loss from equity method investment (1,018) (1,542) (1,561)
Loss before income taxes (50,908) (82,059) (73,144)
Income tax expense 67 201 75
Net loss $ (50,975) $ (82,260) $ (73,219)
Net loss per share—basic and diluted (in dollars per share) $ (1.43) $ (2.56) $ (2.70)
Weighted average number of common shares used in net loss per share—basic and diluted (in shares) 35,675,000 32,148,000 27,085,000
Net loss $ (50,975) $ (82,260) $ (73,219)
Other comprehensive loss:      
Unrealized gain (loss) on available-for-sale securities 33 110 (144)
Comprehensive loss $ (50,942) $ (82,150) $ (73,363)