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Stock-Based Compensation - Stock Options Schedule (Details) - USD ($)
$ / shares in Units, $ in Thousands
 3 Months Ended 6 Months Ended 12 Months Ended
Jun. 30, 2018
Jun. 30, 2017
Jun. 30, 2017
Dec. 31, 2017
Dec. 31, 2016
Shares          
Outstanding at the beginning of the period (in shares)     4,611,392 4,611,392  
Granted (in shares) 1,179,877 2,183,106 4,015,356 4,386,856  
Forfeited (in shares)       (3,252,433)  
Outstanding at the end of the period (in shares)       5,745,815 4,611,392
Exercisable at the end of the period (in shares)       2,370,335  
Vested and expected to vest at the end of the period (in shares)       5,745,815  
Weighted average exercise price per share          
Outstanding at the beginning of the period (in USD per share)     $ 14.42 $ 14.42  
Granted (in dollars per share) $ 0.96 $ 1.46 $ 1.51 1.51  
Forfeited (in dollars per share)       9.63  
Outstanding at the end of period (in USD per share)       7.28 $ 14.42
Exercisable at the end of the period (in dollars per share)       13.37  
Vested and expected to vest at the end of the period (in dollars per share)       $ 7.28  
Weighted average remaining contractual term (years)          
Outstanding       8 years 3 months 26 days 8 years 2 months 23 days
Exercisable at the end of the period       7 years 29 days  
Vested and expected to vest at the end of the period       8 years 3 months 26 days  
Aggregate intrinsic value (in thousands)          
Outstanding       $ 43 $ 45
Exercisable at the end of period       42  
Vested and expected to vest at the end of the period       $ 43