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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
 3 Months Ended
Mar. 31, 2018
Mar. 31, 2017
Operating activities    
Net loss $ (1,356,774) $ (729,575)
Adjustments to reconcile net loss to net cash used in operating activities:    
Amortization 4,952 5,007
Stock-based services expense 254,437
Non-cash interest or non-cash interest on principal 54,116 17,887
Non-cash discount amortization on convertible promissory notes 138,918 178,541
Note issuance costs attributed to warrant liability 15,803
Revaluation of premium conversion derivatives 4,032 183
Revaluation of warrant liability (123,992) (215)
Loss on short-term notes extinguishment 186,220
Change in assets and liabilities:    
Prepaid expenses 53,823
Accrued expenses 246,822 107,627
Net cash used in operating activities (591,269) (350,919)
Financing activities    
Proceeds from issuance of convertible promissory notes 236,136 192,427
Proceeds from issuance of warrants associated with short-term and convertible promissory notes 238,864 182,693
(Repayment) proceeds from short term unsecured loan 115,000 (50,000)
Issuance costs related to convertible promissory notes (5,130)
Issuance costs related to warrants (4,870)
Net cash provided by financing activities 590,000 315,120
Net decrease in cash (1,269) (35,799)
Cash at beginning of period 26,467 522,217
Cash at end of period 25,198 486,418
Supplemental non-cash financing and investing transactions:    
Bifurcation of premium conversion derivative related to convertible promissory notes 91,298 72,732
Accrued issuance costs attributed to convertible promissory notes 16,645
Accrued issuance costs attributed to warrant liability $ 15,803