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Income Taxes (Details)
3 Months Ended 6 Months Ended 12 Months Ended
Jun. 30, 2018
Jun. 30, 2017
Jun. 30, 2018
Jun. 30, 2017
Dec. 31, 2017
Dec. 31, 2016
Income Taxes [Abstract]            
Income tax benefit at federal statutory rate         (34.00%) (34.00%)
State income tax, net of federal benefit         (6.50%) (6.40%)
Disqualified interest and other         0.90% 0.60%
Research credits         (1.2)
U.S. tax reform         12.1
Valuation allowance         28.70% 39.80%
Effective tax rate 0.00% 0.00% 0.00% 0.00%