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Consolidated Statements of Operations - USD ($)
9 Months Ended 12 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Dec. 31, 2017
Operating expenses:      
General and administrative $ 2,676,872 $ 1,798,131 $ 2,336,988
Research and development 715,086 500,408 735,333
Total operating expenses 3,391,958 2,298,539 3,072,321
Loss from operations (3,391,958) (2,298,539) (3,072,321)
Interest expense (763,065) (1,057,024) (1,395,138)
Net change in fair value for the warrant liability and premium conversion derivatives 336,596 (77,505) (240,053)
Loss on note extinguishments, net (1,314,487) (350,914)
Net loss $ (5,132,914) $ (3,433,068) $ (5,058,426)
Net loss per share:      
Basic and diluted $ (0.61) $ (0.55) $ (0.77)
Number of shares used in per share calculations:      
Basic and diluted 8,420,529 6,217,076 6,610,072