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Income Taxes (Tables)
9 Months Ended
Sep. 30, 2018
Income Tax Disclosure [Abstract]  
Schedule of reconciliation of income tax computed at the statutory federal income tax rate

   2018   2017 
Income tax benefit at federal statutory rate   (21.0)%   (34.0)%
State income tax, net of federal benefit   (7.7)   (6.5)
Warrant expense   9.4    10.6 
Disqualified interest and other   1.0    0.9 
Research credits   (1.5)   (1.2)
U.S. tax reform       8.3 
Valuation allowance   19.8    21.9 
Effective tax rate   %   %
Schedule of deferred tax assets and liabilities

   2018   2017 
Deferred tax assets:        
Federal and state operating loss carryforwards  $1,837,375   $871,371 
Acquired intangibles   10,116    5,433 
Accruals   73,763    64,151 
Convertible notes   28,863    81,904 
Research and development credit carryforwards   140,553    63,197 
Stock-based compensation   24,598    19,821 
Total deferred tax assets   2,115,268    1,105,877 
Valuation allowance   (2,115,268)   (1,105,877)
Net deferred tax assets  $   $