    <SEC-DOCUMENT>0001213900-21-052507-index.html : 20211013
    <SEC-HEADER>0001213900-21-052507.hdr.sgml : 20211013
    <ACCEPTANCE-DATETIME>20211012203333
    ACCESSION NUMBER:		0001213900-21-052507
    CONFORMED SUBMISSION TYPE:	424B5
    PUBLIC DOCUMENT COUNT:		4
    FILED AS OF DATE:		20211013
    DATE AS OF CHANGE:		20211012

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			NEUROONE MEDICAL TECHNOLOGIES Corp
    		CENTRAL INDEX KEY:			0001500198
    		STANDARD INDUSTRIAL CLASSIFICATION:	SURGICAL & MEDICAL INSTRUMENTS & APPARATUS [3841]
    		IRS NUMBER:				270863354
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			0930

    	FILING VALUES:
    		FORM TYPE:		424B5
    		SEC ACT:		1933 Act
    		SEC FILE NUMBER:	333-256830
    		FILM NUMBER:		211319876

    	BUSINESS ADDRESS:
    		STREET 1:		7599 ANAGRAM DR
    		CITY:			EDEN PRAIRIE
    		STATE:			MN
    		ZIP:			55344
    		BUSINESS PHONE:		(952) 426-1383

    	MAIL ADDRESS:
    		STREET 1:		7599 ANAGRAM DR
    		CITY:			EDEN PRAIRIE
    		STATE:			MN
    		ZIP:			55344

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	Original Source Entertainment, Inc.
    		DATE OF NAME CHANGE:	20100830
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>424B5
    <SEQUENCE>1
    <FILENAME>f424b51021_neuroone.htm
    <DESCRIPTION>PROSPECTUS
    <TEXT>
    Document 1 - file: f424b51021_neuroone.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>2
    <FILENAME>tneuro_logo.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 2 - file: tneuro_logo.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>timage_001.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 3 - file: timage_001.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>timage_002.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 4 - file: timage_002.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>